Which of the following is a contraindication to bupropion?

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Prepare for the Certified Addictions Registered Nurse (CARN) Advanced Practice Test. Utilize flashcards and multiple-choice questions, complete with hints and explanations. Boost your readiness for the exam!

Multiple Choice

Which of the following is a contraindication to bupropion?

Explanation:
A seizure history is a contraindication to using bupropion because this medication lowers the seizure threshold. Bupropion acts as a dopamine and norepinephrine reuptake inhibitor, and at higher doses it can increase neuronal excitability, raising the risk of seizures. In someone with a prior seizure, this risk is unacceptably high, so it should not be prescribed. Hypertension, diabetes, and anxiety are not absolute contraindications. Bupropion can cause tachycardia or elevated blood pressure in some patients and may transiently worsen anxiety for others, but none of these conditions alone prevents its use.

A seizure history is a contraindication to using bupropion because this medication lowers the seizure threshold. Bupropion acts as a dopamine and norepinephrine reuptake inhibitor, and at higher doses it can increase neuronal excitability, raising the risk of seizures. In someone with a prior seizure, this risk is unacceptably high, so it should not be prescribed.

Hypertension, diabetes, and anxiety are not absolute contraindications. Bupropion can cause tachycardia or elevated blood pressure in some patients and may transiently worsen anxiety for others, but none of these conditions alone prevents its use.

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