Which is a common cardiovascular symptom of opioid withdrawal?

• A. Hypertension
• B. Hypotension
• C. Bradycardia
• D. Hypothermia

Answer: (A)

Opioid withdrawal triggers autonomic hyperactivity as the body compensates for the sudden loss of opioid signaling. This surge in sympathetic activity increases catecholamine release, leading to higher vascular tone and cardiac output. That combination commonly shows up as hypertension, a key cardiovascular change during withdrawal, often alongside tachycardia and sweating.

The other options don’t fit as well. Hypotension would suggest reduced vascular resistance or volume depletion not typical of withdrawal. Bradycardia is more aligned with opioid effects or overdose rather than withdrawal. Hypothermia isn’t a typical withdrawal sign; autonomic activation more often presents with sweating and possible feverish-like symptoms.