Daily naltrexone dosing for AUD is which?

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Prepare for the Certified Addictions Registered Nurse (CARN) Advanced Practice Test. Utilize flashcards and multiple-choice questions, complete with hints and explanations. Boost your readiness for the exam!

Multiple Choice

Daily naltrexone dosing for AUD is which?

Explanation:
Daily oral naltrexone dosing for AUD is 50 mg once daily. This amount provides sufficient mu-opioid receptor blockade to blunt the reinforcing effects of alcohol and help reduce cravings, while maintaining stable plasma levels over a 24-hour period for reliable protection each day. A dose of 2 mg daily is far too low to achieve effective receptor blockade, and 25 mg twice daily isn’t the standard regimen and hasn’t shown a clear advantage over a single daily dose. There is a long-acting injectable option given monthly, but that is a different formulation and not a daily oral schedule.

Daily oral naltrexone dosing for AUD is 50 mg once daily. This amount provides sufficient mu-opioid receptor blockade to blunt the reinforcing effects of alcohol and help reduce cravings, while maintaining stable plasma levels over a 24-hour period for reliable protection each day. A dose of 2 mg daily is far too low to achieve effective receptor blockade, and 25 mg twice daily isn’t the standard regimen and hasn’t shown a clear advantage over a single daily dose. There is a long-acting injectable option given monthly, but that is a different formulation and not a daily oral schedule.

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