Bupropion (Wellbutrin) increases which neurotransmitters?

Unlock all questions

This demo includes only 20 questions. Upgrade to access hundreds of questions, flashcards, exam simulations, and disable ads.

Full question bankExam simulationsFlashcards
From $25.99Unlock all

Prepare for the Certified Addictions Registered Nurse (CARN) Advanced Practice Test. Utilize flashcards and multiple-choice questions, complete with hints and explanations. Boost your readiness for the exam!

Multiple Choice

Bupropion (Wellbutrin) increases which neurotransmitters?

Explanation:
Bupropion works by blocking the reuptake of dopamine and norepinephrine, which increases their availability in the synaptic cleft. This makes it a dopamine and norepinephrine reuptake inhibitor (NDRI). Because of this mechanism, the drug primarily boosts those two neurotransmitters, rather than serotonin or other systems. It also has some nicotinic receptor antagonism, which helps with smoking cessation, but the key effect relevant to its antidepressant action and stimulant-like activation is the increased dopamine and norepinephrine. So, the neurotransmitters most clearly increased by bupropion are dopamine and norepinephrine.

Bupropion works by blocking the reuptake of dopamine and norepinephrine, which increases their availability in the synaptic cleft. This makes it a dopamine and norepinephrine reuptake inhibitor (NDRI). Because of this mechanism, the drug primarily boosts those two neurotransmitters, rather than serotonin or other systems. It also has some nicotinic receptor antagonism, which helps with smoking cessation, but the key effect relevant to its antidepressant action and stimulant-like activation is the increased dopamine and norepinephrine. So, the neurotransmitters most clearly increased by bupropion are dopamine and norepinephrine.

More Multiple Choice Questions
Subscribe

Get the latest from Passetra

You can unsubscribe at any time. Read our privacy policy