Bupropion is commonly used to treat which condition?

• A. Tobacco use disorder
• B. Alcohol use disorder
• C. Opioid use disorder
• D. Cannabis use disorder

Answer: (A)

Bupropion helps people quit smoking because it raises both norepinephrine and dopamine in brain pathways that drive mood and reward, which lowers nicotine withdrawal symptoms and cravings. Its antidepressant effects can also support mood during cessation, making it a commonly used option for tobacco use disorder. It isn’t the typical pharmacotherapy for alcohol, opioid, or cannabis use disorders, where other medications such as naltrexone or acamprosate (for alcohol) and methadone or buprenorphine (for opioid) are more appropriate. Keep in mind safety considerations: avoid if there is a history of seizures or certain eating disorders, and monitor for insomnia or rises in blood pressure.